The New Science of Weight Loss
Chances are, you’re carrying this around. And we’ve found a better way to get
rid of it
By: Lou Schuler
If there’s a god of weight loss, he’s probably laughing.
For the past 40 years, virtually every weight-loss model has been based on the
same principles, and virtually all of them have been wrong. The experts intoned,
“Eat less, exercise more.” They said that weight loss is all about “calories in,
calories out.” They informed us that a pound of fat contained roughly 3,500
calories, so if you simply deleted 500 calories from your daily meals or
increased your daily exercise by 500 calories, or some combination thereof,
you’d lose a pound of fat a week. And if you wanted to lose 2 pounds a week, you
just had to double your savings to 1,000 calories a day.
Which is exactly how an anorexic would approach the problem: Starve and strain
until you get that perfect, fat-free body, regardless of the muscle you lose or
the damage you inflict on your metabolism. And if Lara Flynn Boyle has the body
you want, go right ahead and try it.
For the benefit of the rest of you, I want to make two arguments, supported by
the latest nutrition and exercise science. That science points toward a new,
improved approach to weight loss.

First, I want to show that when you eat has a
profound effect on how your body deals with the calories you feed it. And I want
to present a more sophisticated approach to exercise. This approach not only
preserves your body’s metabolism, the key to weight control, but also makes more
productive use of your precious time and energy.
Grab a bite to eat, then chew on this.
Part 1: Energy Balance Is The Key To Weight Control
If you want to understand energy balance in an instant, think of your body as a
car that operates 24 hours a day, says Dan Benardot, Ph.D., R.D., a nutrition
researcher at Georgia State University in Atlanta. You would never expect your
car to get you from one place to the next without systematic refueling, just as
you know there’s no point in putting more gas in the tank than it’s designed to
hold. But that’s how many of us operate our bodies.
We try to run on empty for hours, then dump in more fuel than we can handle.
Benardot’s research shows how self-destructive this strategy is.
Let’s say you really want to lose fat, and decide to jog first thing in the
morning, on an empty stomach. “The easiest way to get energy is to break down
muscle mass,” Benardot says. Your body can convert specific amino acids–the
building blocks of muscle–to glucose, the sugar that powers human activity.
“Someone running before eating may actually be breaking down the very tissue
he’s trying to improve. Sounds counterproductive to me.”
Call it the “muscle loss” diet.
The second way is probably more typical of most of us. You can call this one the
“fat gain” diet. You wait a long time between meals, and then, when you’re
ravenously hungry, you wipe out an entire buffet line. This guarantees that
you’ll get a larger surge of the hormone insulin than you ordinarily would. That
means more fat storage.
And you can probably combine the “muscle loss” and “fat gain” strategies and
turn your body into a perfect muscle-burning, fat-storing machine. Hard exercise
slows down appetite in the short term, but as you get used to it, your appetite
matches your exertion level. So if you go out and run 10 miles on an empty
stomach, then eat enough to fuel a 15-mile run, the net effect is that you’ve
lost muscle on the run and gained fat from the postrun meal.
Energy balance, the focus of Benardot’s research, is the answer to both of these
dilemmas. The athletes in his studies get the best results when they stay within
300 to 500 calories of perfect energy balance throughout the day.
This means . . .
1. Eat as soon as you wake up in the morning.
2. Make sure you eat something before you exercise, no matter what time of day
it is.
Not only does the food prevent your muscle tissue from becoming cardio chow, but
it increases the number of calories you burn during and after exercise. A 1992
study at Arnot-Ogden Medical Center in Elmira, New York, shows that exercise
following a meal enhances metabolism.
3. Eat soon after exercising, when your body has depleted its energy stores. Act
fast, or you’ll start burning muscle for energy.
4. Eat a total of five to six small meals a day.
One of Benardot’s studies showed that athletes who added three daily snacks to
their three squares lost fat and gained muscle, on top of improving in all the
other things that are important to athletes, such as power and endurance. Of
course, you can’t simply add a few hundred calories to your diet and lose
weight, but you can redistribute your daily calories so you’re eating more often
but consuming less at individual meals.
However you do it, it’s clear to Benardot that the worst strategy is cutting out
tons of calories indiscriminately in hopes of sudden, dramatic weight loss. “If
you’re more subtle and try to lose a pound a week or 1 pound in 2 weeks, not
only can you do it, but you’ll be less likely to regain the weight,” he says.
Part 2: Energy Flux Drives Your Metabolism
You probably know that your resting metabolism–the number of calories you burn
in the 23 hours a day when you aren’t exercising–slows as you get older. That’s
the reason most of us gain weight as we age. However, a 2001 University of
Colorado study found that older men who exercise and eat as much as younger men
have similar metabolic rates.
This doesn’t mean you have to work out the way you did a decade ago, or drop
your Healthy Choice dinners in favor of the Big Macs of your youth. It just
means that the number of calories coming into your body has an influence on the
number of calories going out. Two mechanisms are at work.
The first is what textbooks call the “thermic effect of feeding”–the caloric
cost of digesting the food you eat. On average, it accounts for about 10 percent
of the total calories you burn each day. But that’s just an average. It can dip
if you eat less, and it can rise if you eat more, or eat more often, or eat
different types of foods.
The second is the effect of exercise and other movement throughout the day. This
is the part of the equation most weight-loss experts focus on. But if you
combine increased feeding with increased movement, you increase your “energy
flux,” and this is the key to maintaining a fast, muscle-friendly, fat-starving
It’s no more complicated than balancing your checkbook, which (in my experience,
anyway) is a lot easier to do when you have plenty of money coming in than it is
when you’re unemployed. Some types of food are better at creating energy flux
than others. Protein, for example, takes more calories to digest than either
carbohydrates or fat. And studies show that protein from animal sources (steak!)
seems to have a bigger bang than soy protein (tofu).
The type of exercise you do also affects energy flux. Strength training, for
example, can create enormous increases in your resting metabolic rate that last
a day or two after your workout. Aerobic exercise doesn’t do much, if anything,
to boost your metabolic rate, beyond the calories you burn while aerobicizing
and for a brief time afterward.
This brings up the obvious question: What is it about strength training that
creates a multiday afterburn? The most important factor is muscle repair. An
hour of iron therapy causes your muscle tissues to break down at a higher rate
than normal. But, thanks to the protein you’ve eaten after your workout, your
muscles are also rebuilding themselves faster than they ordinarily would. So you
have energy flux going on within the muscles themselves. A 2003 Finnish study
found that protein synthesis (the process that builds bigger muscles) increases
by 21 percent 3 hours after a workout, while protein breakdown increases 17
percent. The combination is called “protein turnover,” and it uses up a lot of
The type of workout that raises metabolism in studies is usually long and hard,
although a recent Ohio University study used a short-but-hard workout and got
similar results. The men in the study did circuits of power cleans, bench
presses, and squats (a circuit being one exercise right after the other) for 31
minutes. They were still burning more calories than normal 38 hours after the
Part 3: Diet And Exercise Turn Your Body Into A Fat-Burning Machine
Efficiency is a good thing when you’re talking about running your business. But
it sucks the benefits out of your diet and workout. The more efficient your body
is at exercise, the fewer calories it burns. Think of the guy in your health
club who does the exact same workout every time you see him, with the exact same
weights. He never looks better from one year to the next because his body has
become so efficient at doing those moves that it doesn’t need to grow bigger
muscles or burn more fat in order to finish the workout.
Science has shown us some good strategies for making exercise less efficient:
Strength training.
You can make your lifts less efficient in two ways–by increasing the amount of
weight you’re lifting, or by choosing exercises that are more challenging to
your balance and coordination.
Let’s say your maximum bench press is 200 pounds. Lifting 200 pounds once is
very inefficient; your body throws every muscle fiber into it. But lifting 50
pounds four times is very easy, and thus efficient. The metabolic cost of
lifting 200 pounds once is thus greater than the cost of lifting 50 pounds four
times. Doing maximum-effort sets of three to six repetitions with, say, 165 to
185 pounds would be a better way to overload your metabolism than doing sets of
10 to 12 reps with lighter weights.
The least efficient lifts are those in which the weight is over your head. This
would include standing shoulder presses, as well as exercises such as squats or
lunges in which you hold a weight overhead. So instead of doing shoulder presses
in a machine or sitting on a bench, stand and crank them out.
Endurance exercise.
No surprises here: If you perform intervals, in which you go hard, then easy,
then hard again, you take the efficiency out of your run, swim, or ride. You can
call this the “Old Science of Weight Loss,” since studies have shown the
fat-burning benefits of intervals since the early ’90s.
Your diet, too, can be made less efficient, and thus more calorically costly. I
showed in the previous section how a higher-protein diet kicks up your
metabolism, a sign that your body is burning calories inefficiently. But if that
protein comes in the form of high-calcium dairy–milk, yogurt, cheese–you take
the inefficiency one giant step further.
Part 4: Put It All Together, Now
That’s a lot of science, which I now give you permission to forget. Just
remember these five rules that derive from it.
1. Eat five or six times a day, avoiding large gaps between meals and snacks.
Don’t allow yourself to get ravenously hungry, and don’t stuff yourself. If you
find you’re slipping into a bad mood before a meal, that’s a pretty good sign
you’ve waited too long to eat.
2. Eat some protein at every meal and snack, and some calcium-rich dairy at
several of them.
3. Always eat something shortly before exercising; you’ll burn more calories
that way. Then eat something soon after. This will speed up the repair process,
which also costs your body some caloric capital.
4. Lift weights two to four times a week, focusing on the largest muscle groups.
Three total-body workouts a week is ideal for creating a metabolic challenge;
that way, you use all your big muscles every time you hit the gym.
5. Try to do something active on two or three of your nonlifting days. If you
have the energy, interval workouts are best. But if these additional workouts
leave you feeling wiped, it’s far better to conserve your energy for three tough
strength workouts a week, rather than spread it out over six half-assed exercise
I wish I could conclude this by telling you that weight loss is fast and easy,
rather than slow and strenuous. But the exciting news is that science has found
a straighter path to steady, successful weight loss–no starvation or death
marches required. Here’s wishing you a happy, less efficient new year.

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